Pathomorphological changes in the organs of the peripheral immune system in mycobacteriosis of cattle

Conducting routine allergy tests of cattle with a simultaneous sample in TB-prone farms is necessary to confirm the stage epizootic process. The purpose research – explore pathomorphological changes cows upon detection para allergic reactions during diagnostic testing for tuberculosis. diagnosis tuberculosis animals was performed comprehensively using all methods control provided guidelines epidemiological, clinical, allergic, pathological, histomorphological, bacteriological and biological. It allowed establishing that tuberculin were paraallergic nature, caused by nontuberculous mycobacteria or so-called atypical mycobacteria. determined reacted positively an mycobacterial allergen sent slaughter purposes did not demonstrate pathological characteristic However, (granulomatous foci, atrophy lymphoid epithelioid tissue, hyperplasia varying intensity dotted haemorrhages cortical zone) observed many lymph nodes, including mediastinal, mesenteric, pharyngeal mandibular indicating active infectious process body Therewith, several nodes histomorphological examination: development primary nodules lymphocytes reticular tissue reactive centres, degradation necrosis lymphocytes, establishment cellular detritus centre capsules elements around nodules, etc., which can be used patterns pathology and, indirectly, mechanism sensitisation cow’s body, therefore nature animals. obtained results are important timely identification at level complex organs tissues due penetration mycobacteria, key successful foci mycobacteriosis their effective prevention